⭐ 1. Strength

• Zyprexa = Stronger
• Seroquel = Milder

Zyprexa works faster and harder on symptoms.

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⭐ 2. What They Treat Best

Seroquel:

• Anxiety
• Bipolar depression
• Sleep problems
• Mild–moderate psychosis

Zyprexa:

• Severe mania
• Strong hallucinations/delusions
• Aggression
• When fast control is needed

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⭐ 3. Side Effects

Seroquel:

• Sleepy
• Some weight gain
• Dry mouth

Zyprexa:

• A lot of weight gain
• Very sleepy
• Higher risk of diabetes

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⭐ 4. How They Work on the Brain

Zyprexa:

• Blocks dopamine + serotonin strongly
• More powerful effect

Seroquel:

• Blocks dopamine lightly
• Blocks serotonin moderately
• Feels smoother and gentler

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⭐ 5. How They Feel

Seroquel:

• Calming
• Good for sleep
• Easier to function on

Zyprexa:

• Heavy, strong
• Very sedating
• Fast symptom relief

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✅ Very Short Summary

• Need strong, fast antipsychotic treatment? → Zyprexa
• Need calming, sleep, depression help, fewer metabolic issues? → Seroquel

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Here is a clean, simple comparison chart for Seroquel vs Zyprexa:

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📊 Seroquel (Quetiapine) vs Zyprexa (Olanzapine) – Comparison Chart

Category	Seroquel	Zyprexa
Strength	Moderate	Very strong
Speed of effect	Slow–medium	Fast
Best for	Anxiety, sleep, bipolar depression, milder psychosis	Severe mania, strong psychosis, aggression
Sedation	High	Very high
Weight gain	Medium–high	Very high
Diabetes risk	Medium	High
Dopamine blocking	Weak	Strong
Serotonin blocking	Moderate	Strong
Functioning during day	Easier	Harder (heavier feeling)
Use at night	Very good	Very good but heavy
Withdrawal risk	Mild if stopped suddenly	Moderate
Common reason doctors choose it	Calming, sleep, depression	Fast power, strong control

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⭐ One-Sentence Summary

Seroquel = gentler, calming, better for depression & sleep.
Zyprexa = stronger, heavier, better for severe mania & psychosis.

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