🔵 Zyprexa (Olanzapine)

Serotonin (5-HT2A)

• Strong blocker
• Strong serotonin effect =
  ✔ heavy sedation
  ✔ big appetite increase
  ✔ strong mood stabilization

Dopamine (D2)

• Strong blocker
• Strong dopamine effect =
  ✔ powerful antipsychotic
  ✔ fast control of mania & hallucinations

➡️ Overall:
Zyprexa hits BOTH serotonin and dopamine strongly.
It is one of the most powerful atypical antipsychotics.

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🟣 Seroquel (Quetiapine)

Serotonin (5-HT2A)

• Moderate blocker
• Helps with:
  ✔ calming
  ✔ mood stabilization
  ✔ depression (especially from its metabolite, norquetiapine)

Dopamine (D2)

• Weak blocker
• Means:
  ✔ milder antipsychotic strength
  ✔ gentler effect
  ✔ fewer movement side effects
  ✔ better for sleep and anxiety

➡️ Overall:
Seroquel hits serotonin moderately and dopamine lightly.
It is softer and less “heavy” than Zyprexa.

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⭐ Very Simple Summary

Medication	Serotonin Effect	Dopamine Effect	Overall Strength
Zyprexa	Strong	Strong	Very strong
Seroquel	Moderate	Weak	Gentle–moderate

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If you want, I can make:
✔ A visual chart
✔ A receptor-binding percentage chart
✔ A simple analogy (like “Zyprexa = hammer, Seroquel = pillow”)
✔ A comparison focusing on depression, mania, anxiety, or sleep

Just tell me!